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Altitude simulation programs work to combat Diabetes in a similar fashion to exercise. Many of the benefits of exercise come from the creation of a hypoxic state within the body. While normoxic exercise may only bring the body’s blood oxygen saturation (Sa02) to around 95%, hypoxic therapy can more efficiently reduce this value to 80-85% and lower. This distinction provides hypoxic therapy with a unique advantage over exercise in the promotion of:
• Glucose uptake into cells
• Weight-loss
• Decreased blood pressure
• Reduced cholesterol levels.
The mechanism for these effects is as follows. An acute state of hypoxia within the cells leads to insufficient oxygen for energy production. In turn, the cell increases production of non-insulin dependent glucose transporters, allowing more glucose to be taken into cells and transformed into energy. This reaction is vital for diabetics who either don’t produce enough insulin or can’t use it to promote glucose uptake into cells.




